Slope Factors for Carcinogens from Health Canada

View Slope Factors from: Health Canada | US EPA


Chemical Name CAS Number Chemical Class Oral slope factor
(mg/kg-d)-1
Inhalation slope factor
(mg/kg-d)-1
Inhalation unit risk
(mg/m3)-1
Source Special
2,4-D 94-75-7 organic


HC1
Aldicarb 116-06-3 organic


HC1
Aldrin 309-00-2 organic HC1
Aniline 62-53-3 organic HC1
Anthracene 120-12-7 organic 0.23 0.0137 0.0031 IRIS/HC2 PAH-Carcinogenic
Arsenic 7440-38-2 inorganic 1.8 28 6.4 HC1
Atrazine + metabolites 1912-24-9 organic HC1
Azinphos-methyl 86-50-0 organic


HC1
Barium 7440-39-3 inorganic HC1
Bendiocarb 22781-23-3 organic HC1
Benz[a]anthracene 56-55-3 organic 0.23 0.0137 0.0031 HC2 PAH-Carcinogenic
Benzene 71-43-2 organic 0.226 0.0146 0.0033 HC1
Benzo(a)pyrene 50-32-8 organic 2.3 0.137 0.03 HC1 PAH-Carcinogenic
Benzo(b)fluoranthene 205-99-2 organic 0.23 0.0137 0.0031 HC2 PAH-Carcinogenic
Benzo(g,h,i)perylene 191-24-2 organic 0.023 0.00137 0.00031 HC2 PAH-Carcinogenic
Benzo(j)fluoranthene 205-82-3 organic 0.23 0.0137 0.0031 HC2 PAH-Carcinogenic
Benzo(k)fluoranthene 207-08-9 organic 0.23 0.0137 0.0031 HC2 PAH-Carcinogenic
Bis(2-ethyl-hexyl) phthalate 117-81-7 organic HC1
Bis(Chloro-methyl) ether 542-88-1 organic 41.3 9.43 HC1
Boron (and borates) 7440-42-8 inorganic


HC1
Bromoxynil 1689-84-5 organic HC1
Cadmium 7440-43-9 inorganic 42.9 9.8 HC1
Carbaryl 63-25-2 organic


HC1
Carbofuran 1563-66-2 organic HC1
Carbon tetrachloride 56-23-5 organic 0.049 HC1
Chloramine, mono 10599-90-3 organic


HC1
Chlorobenzene 108-90-7 organic HC1
Chlorpyrifos 2921-88-2 organic HC1
Chromium, hexavalent 18540-29-9 inorganic
331 75.8 HC1
Chromium, total 7440-47-3 inorganic 47.6 10.9 HC1
Chrysene 218-01-9 organic 0.023 0.00137 0.00031 HC2 PAH-Carcinogenic
Copper 7440-50-8 inorganic


HC1
Cumene (isopropylbenzene) 98-82-8 organic IRIS
Cyanazine 21725-46-2 organic HC1
Cyanide, free (CN- + HCN) 57-12-5 inorganic


HC1
DDT (DDT, p,p'-) 50-29-3 organic HC1
Diazinon 333-41-5 organic HC1
Dibenz(a,h)anthracene 53-70-3 organic 0.23 0.0137 0.0031 HC2 PAH-Carcinogenic
Dibromoethane, 1,2- 106-93-4 organic 2 0.6 IRIS
Dibutyl phthalate 84-74-2 organic HC1
Dicamba 1918-00-9 organic


HC1
Dichlorobenzene, 1,2- 95-50-1 organic HC1
Dichlorobenzene, 1,4- 106-46-7 organic HC1
Dichlorobenzidine, 3,3'- 91-94-1 organic 0.0676

HC1
Dichloroethane, 1,2- 107-06-2 organic 0.00806 HC1
Dichloroethylene, 1,1 75-35-4 organic HC1
Dichloromethane 75-09-2 organic 0.000079 0.000099 0.000023 HC1
Dichorophenol, 2,4- 120-83-2 organic HC1
Diclofop-methyl 51338-27-3 organic HC1
Dieldrin 60-57-1 organic


HC1
Dimethoate 60-51-5 organic HC1
Dinoseb 88-85-7 organic HC1
Dioxane, 1,4- 123-91-1 organic 0.11

HC1
Diquat 2764-72-9 organic HC1
Diuron 330-54-1 organic HC1
Ethylbenzene 100-41-4 organic


IRIS
Fluoranthene 206-44-0 organic 0.0023 0.000137 0.000031 HC2 PAH-Carcinogenic
Fluorene 86-73-7 organic IRIS
Fluoride, inorganic (F-) 16984-48-8 inorganic


HC1
Glyphosate 1071-83-6 organic HC1
Hexachlorobenzene 118-74-1 organic HC1
Indeno(1,2,3-c,d)pyrene 193-39-5 organic 0.23 0.0137 0.0031 HC2 PAH-Carcinogenic
Lead 7439-92-1 inorganic HC1
Malathion 121-75-5 organic HC1
Manganese 7439-96-5 inorganic


HC1
Mercury, inorganic (ionic) NA inorganic HC1
Mercury, vapour NA inorganic HC1
Methoxychlor 72-43-5 organic


HC1
Methyl mercury 22967-92-6 organic HC1
Methyl methacrylate 80-62-6 organic HC1
Methyl t-butyl ether (MTBE) 1634-04-4 organic


HC1
Metolachlor 51218-45-2 organic HC1
Metribuzin 21087-64-9 organic HC1
Molybdenum 7439-98-7 inorganic


HC1
Naphthalene 91-20-3 organic IRIS
Naphthalene, 2-Methyl 91-57-6 organic IRIS
Nickel (II) chloride 7718-54-9 inorganic


HC1
Nickel (II) oxide 1313-99-1 inorganic HC1
Nickel (II) sulfate 7786-81-4 inorganic HC1
Nickel (III) subsulfide 12035-72-2 inorganic


HC1
Nickel, metallic 7440-02-0 inorganic HC1
Nickel, oxidic/sulphidic/soluble NA inorganic 5.5 1.3 HC1
Nickel, soluble NA inorganic
3.1 0.71 HC1
Nitrilotriacetic acid (NTA) 139-13-9 organic HC1
Paraquat (as dichloride) 1910-42-51 organic HC1
Parathion 56-38-2 organic


HC1
Pentachlorobenzene 608-93-5 organic HC1
Pentachlorophenol 87-86-5 organic HC1
Phenanthrene 85-01-8 organic 0.0023 0.000137 0.000031 HC2 PAH-Carcinogenic
Phenol 108-95-2 organic HC1
Phorate 298-02-2 organic HC1
Picloram 1918-02-1 organic


HC1
Polychlorinated Biphenyls (total) NA organic HC1
Pyrene 129-00-0 organic IRIS
Selenium 7782-49-2 inorganic


HC1
Simazine 122-34-9 organic HC1
Styrene 100-42-5 organic HC1
Terbufos 13071-79-9 organic


HC1
Tetrachlorobenzene, 1,2,3,4- 634-66-2 organic HC1
Tetrachlorobenzene, 1,2,3,5- 634-90-2 organic HC1
Tetrachlorobenzene, 1,2,4,5- 95-94-3 organic


HC1
Tetrachloro-dibenzofuran, 2,3,7,8- 51207-31-9 organic HC1
Tetrachloro-dibenzo-p-dioxin, 2,3,7,8- 1746-01-6 organic HC1
Tetrachloroethylene (PCE) 127-18-4 organic


HC1
Tetrachlorophenol, 2,3,4,6- 58-90-2 organic HC1
Toluene 108-88-3 organic HC1
Tributyltin Oxide 56-35-9 organic


IRIS
Trichlorobenzene, 1,2,3- 87-61-6 organic HC1
Trichlorobenzene, 1,2,4- 120-82-1 organic HC1
Trichlorobenzene, 1,3,5- 108-70-3 organic


HC1
Trichloroethylene (TCE) 79-01-6 organic 0.00025 0.0027 0.00061 HC1
Trichlorophenol,2,4,6- 88-06-2 organic 0.02 HC1
Trichloropropane, 1,2,3- 96-18-4 organic


IRIS
Trifluralin 1582-09-8 organic HC1
Uranium (non-radiological) 7440-61-1 inorganic HC1
Vinyl chloride 75-01-4 organic 0.26

HC1
Xylenes (total) 1330-20-7 organic HC1
Zinc 7440-66-6 inorganic


HC1

sources:
HC1 -  Health Canada. 2007 (draft). Federal Contaminated Site Risk Assessment in Canada. Part II: Health Canada Toxicological Reference Values (TRVs). Version 2.0.
HC2 - Health Canada. 2007 (draft). Federal Contaminated Site Risk Assessment in Canada. Part I: Guidance on Human Health Preliminary Quantitative Risk Assessment. Version 2.0.
IRIS - US EPA. 2007. Integrated Risk Information System. Online: www.epa.gov/iris
Hatfield Consultants The World Bank funded by the Canadian POPs Trust Fund through the      
Canadian International Development Agency