Slope Factors for Carcinogens from Health Canada
View Slope Factors from: Health Canada | US EPA
| Chemical Name | CAS Number | Chemical Class |
Oral slope factor (mg/kg-d)-1 |
Inhalation slope factor (mg/kg-d)-1 |
Inhalation unit risk (mg/m3)-1 |
Source | Special |
| 2,4-D | 94-75-7 | organic |
|
|
|
HC1 |
|
| Aldicarb | 116-06-3 | organic |
|
|
|
HC1 |
|
| Aldrin | 309-00-2 | organic | HC1 | ||||
| Aniline | 62-53-3 | organic | HC1 | ||||
| Anthracene | 120-12-7 | organic | 0.23 | 0.0137 | 0.0031 | IRIS/HC2 | PAH-Carcinogenic |
| Arsenic | 7440-38-2 | inorganic | 1.8 | 28 | 6.4 | HC1 | |
| Atrazine + metabolites | 1912-24-9 | organic | HC1 | ||||
| Azinphos-methyl | 86-50-0 | organic |
|
|
|
HC1 |
|
| Barium | 7440-39-3 | inorganic | HC1 | ||||
| Bendiocarb | 22781-23-3 | organic | HC1 | ||||
| Benz[a]anthracene | 56-55-3 | organic | 0.23 | 0.0137 | 0.0031 | HC2 | PAH-Carcinogenic |
| Benzene | 71-43-2 | organic | 0.226 | 0.0146 | 0.0033 | HC1 | |
| Benzo(a)pyrene | 50-32-8 | organic | 2.3 | 0.137 | 0.03 | HC1 | PAH-Carcinogenic |
| Benzo(b)fluoranthene | 205-99-2 | organic | 0.23 | 0.0137 | 0.0031 | HC2 | PAH-Carcinogenic |
| Benzo(g,h,i)perylene | 191-24-2 | organic | 0.023 | 0.00137 | 0.00031 | HC2 | PAH-Carcinogenic |
| Benzo(j)fluoranthene | 205-82-3 | organic | 0.23 | 0.0137 | 0.0031 | HC2 | PAH-Carcinogenic |
| Benzo(k)fluoranthene | 207-08-9 | organic | 0.23 | 0.0137 | 0.0031 | HC2 | PAH-Carcinogenic |
| Bis(2-ethyl-hexyl) phthalate | 117-81-7 | organic | HC1 | ||||
| Bis(Chloro-methyl) ether | 542-88-1 | organic | 41.3 | 9.43 | HC1 | ||
| Boron (and borates) | 7440-42-8 | inorganic |
|
|
|
HC1 |
|
| Bromoxynil | 1689-84-5 | organic | HC1 | ||||
| Cadmium | 7440-43-9 | inorganic | 42.9 | 9.8 | HC1 | ||
| Carbaryl | 63-25-2 | organic |
|
|
|
HC1 |
|
| Carbofuran | 1563-66-2 | organic | HC1 | ||||
| Carbon tetrachloride | 56-23-5 | organic | 0.049 | HC1 | |||
| Chloramine, mono | 10599-90-3 | organic |
|
|
|
HC1 |
|
| Chlorobenzene | 108-90-7 | organic | HC1 | ||||
| Chlorpyrifos | 2921-88-2 | organic | HC1 | ||||
| Chromium, hexavalent | 18540-29-9 | inorganic |
|
331 | 75.8 | HC1 |
|
| Chromium, total | 7440-47-3 | inorganic | 47.6 | 10.9 | HC1 | ||
| Chrysene | 218-01-9 | organic | 0.023 | 0.00137 | 0.00031 | HC2 | PAH-Carcinogenic |
| Copper | 7440-50-8 | inorganic |
|
|
|
HC1 |
|
| Cumene (isopropylbenzene) | 98-82-8 | organic | IRIS | ||||
| Cyanazine | 21725-46-2 | organic | HC1 | ||||
| Cyanide, free (CN- + HCN) | 57-12-5 | inorganic |
|
|
|
HC1 |
|
| DDT (DDT, p,p'-) | 50-29-3 | organic | HC1 | ||||
| Diazinon | 333-41-5 | organic | HC1 | ||||
| Dibenz(a,h)anthracene | 53-70-3 | organic | 0.23 | 0.0137 | 0.0031 | HC2 | PAH-Carcinogenic |
| Dibromoethane, 1,2- | 106-93-4 | organic | 2 | 0.6 | IRIS | ||
| Dibutyl phthalate | 84-74-2 | organic | HC1 | ||||
| Dicamba | 1918-00-9 | organic |
|
|
|
HC1 |
|
| Dichlorobenzene, 1,2- | 95-50-1 | organic | HC1 | ||||
| Dichlorobenzene, 1,4- | 106-46-7 | organic | HC1 | ||||
| Dichlorobenzidine, 3,3'- | 91-94-1 | organic | 0.0676 |
|
|
HC1 |
|
| Dichloroethane, 1,2- | 107-06-2 | organic | 0.00806 | HC1 | |||
| Dichloroethylene, 1,1 | 75-35-4 | organic | HC1 | ||||
| Dichloromethane | 75-09-2 | organic | 0.000079 | 0.000099 | 0.000023 | HC1 |
|
| Dichorophenol, 2,4- | 120-83-2 | organic | HC1 | ||||
| Diclofop-methyl | 51338-27-3 | organic | HC1 | ||||
| Dieldrin | 60-57-1 | organic |
|
|
|
HC1 |
|
| Dimethoate | 60-51-5 | organic | HC1 | ||||
| Dinoseb | 88-85-7 | organic | HC1 | ||||
| Dioxane, 1,4- | 123-91-1 | organic | 0.11 |
|
|
HC1 |
|
| Diquat | 2764-72-9 | organic | HC1 | ||||
| Diuron | 330-54-1 | organic | HC1 | ||||
| Ethylbenzene | 100-41-4 | organic |
|
|
|
IRIS |
|
| Fluoranthene | 206-44-0 | organic | 0.0023 | 0.000137 | 0.000031 | HC2 | PAH-Carcinogenic |
| Fluorene | 86-73-7 | organic | IRIS | ||||
| Fluoride, inorganic (F-) | 16984-48-8 | inorganic |
|
|
|
HC1 |
|
| Glyphosate | 1071-83-6 | organic | HC1 | ||||
| Hexachlorobenzene | 118-74-1 | organic | HC1 | ||||
| Indeno(1,2,3-c,d)pyrene | 193-39-5 | organic | 0.23 | 0.0137 | 0.0031 | HC2 | PAH-Carcinogenic |
| Lead | 7439-92-1 | inorganic | HC1 | ||||
| Malathion | 121-75-5 | organic | HC1 | ||||
| Manganese | 7439-96-5 | inorganic |
|
|
|
HC1 |
|
| Mercury, inorganic (ionic) | NA | inorganic | HC1 | ||||
| Mercury, vapour | NA | inorganic | HC1 | ||||
| Methoxychlor | 72-43-5 | organic |
|
|
|
HC1 |
|
| Methyl mercury | 22967-92-6 | organic | HC1 | ||||
| Methyl methacrylate | 80-62-6 | organic | HC1 | ||||
| Methyl t-butyl ether (MTBE) | 1634-04-4 | organic |
|
|
|
HC1 |
|
| Metolachlor | 51218-45-2 | organic | HC1 | ||||
| Metribuzin | 21087-64-9 | organic | HC1 | ||||
| Molybdenum | 7439-98-7 | inorganic |
|
|
|
HC1 |
|
| Naphthalene | 91-20-3 | organic | IRIS | ||||
| Naphthalene, 2-Methyl | 91-57-6 | organic | IRIS | ||||
| Nickel (II) chloride | 7718-54-9 | inorganic |
|
|
|
HC1 |
|
| Nickel (II) oxide | 1313-99-1 | inorganic | HC1 | ||||
| Nickel (II) sulfate | 7786-81-4 | inorganic | HC1 | ||||
| Nickel (III) subsulfide | 12035-72-2 | inorganic |
|
|
|
HC1 |
|
| Nickel, metallic | 7440-02-0 | inorganic | HC1 | ||||
| Nickel, oxidic/sulphidic/soluble | NA | inorganic | 5.5 | 1.3 | HC1 | ||
| Nickel, soluble | NA | inorganic |
|
3.1 | 0.71 | HC1 |
|
| Nitrilotriacetic acid (NTA) | 139-13-9 | organic | HC1 | ||||
| Paraquat (as dichloride) | 1910-42-51 | organic | HC1 | ||||
| Parathion | 56-38-2 | organic |
|
|
|
HC1 |
|
| Pentachlorobenzene | 608-93-5 | organic | HC1 | ||||
| Pentachlorophenol | 87-86-5 | organic | HC1 | ||||
| Phenanthrene | 85-01-8 | organic | 0.0023 | 0.000137 | 0.000031 | HC2 | PAH-Carcinogenic |
| Phenol | 108-95-2 | organic | HC1 | ||||
| Phorate | 298-02-2 | organic | HC1 | ||||
| Picloram | 1918-02-1 | organic |
|
|
|
HC1 |
|
| Polychlorinated Biphenyls (total) | NA | organic | HC1 | ||||
| Pyrene | 129-00-0 | organic | IRIS | ||||
| Selenium | 7782-49-2 | inorganic |
|
|
|
HC1 |
|
| Simazine | 122-34-9 | organic | HC1 | ||||
| Styrene | 100-42-5 | organic | HC1 | ||||
| Terbufos | 13071-79-9 | organic |
|
|
|
HC1 |
|
| Tetrachlorobenzene, 1,2,3,4- | 634-66-2 | organic | HC1 | ||||
| Tetrachlorobenzene, 1,2,3,5- | 634-90-2 | organic | HC1 | ||||
| Tetrachlorobenzene, 1,2,4,5- | 95-94-3 | organic |
|
|
|
HC1 |
|
| Tetrachloro-dibenzofuran, 2,3,7,8- | 51207-31-9 | organic | HC1 | ||||
| Tetrachloro-dibenzo-p-dioxin, 2,3,7,8- | 1746-01-6 | organic | HC1 | ||||
| Tetrachloroethylene (PCE) | 127-18-4 | organic |
|
|
|
HC1 |
|
| Tetrachlorophenol, 2,3,4,6- | 58-90-2 | organic | HC1 | ||||
| Toluene | 108-88-3 | organic | HC1 | ||||
| Tributyltin Oxide | 56-35-9 | organic |
|
|
|
IRIS |
|
| Trichlorobenzene, 1,2,3- | 87-61-6 | organic | HC1 | ||||
| Trichlorobenzene, 1,2,4- | 120-82-1 | organic | HC1 | ||||
| Trichlorobenzene, 1,3,5- | 108-70-3 | organic |
|
|
|
HC1 |
|
| Trichloroethylene (TCE) | 79-01-6 | organic | 0.00025 | 0.0027 | 0.00061 | HC1 | |
| Trichlorophenol,2,4,6- | 88-06-2 | organic | 0.02 | HC1 | |||
| Trichloropropane, 1,2,3- | 96-18-4 | organic |
|
|
|
IRIS |
|
| Trifluralin | 1582-09-8 | organic | HC1 | ||||
| Uranium (non-radiological) | 7440-61-1 | inorganic | HC1 | ||||
| Vinyl chloride | 75-01-4 | organic | 0.26 |
|
|
HC1 |
|
| Xylenes (total) | 1330-20-7 | organic | HC1 | ||||
| Zinc | 7440-66-6 | inorganic |
|
|
|
HC1 |
|
sources:
HC1 - Health Canada. 2007 (draft). Federal Contaminated Site Risk Assessment in Canada. Part II: Health Canada Toxicological Reference Values (TRVs). Version 2.0.
HC2 - Health Canada. 2007 (draft). Federal Contaminated Site Risk Assessment in Canada. Part I: Guidance on Human Health Preliminary Quantitative Risk Assessment. Version 2.0.
IRIS - US EPA. 2007. Integrated Risk Information System. Online: www.epa.gov/iris
Error: footer could not be retrieved!